You can wipe your orthotics with a damp cloth and a mild detergent. It is not advised to soak your orthotics; however, if they do get wet set them out to air dry. The worse thing that will happen is that the glue will lift, that is easily fixed. Do not expose them to high heat. It is advised to take your orthotics out to let them dry on occasion especially if used on a regular basis or for sports. Remember that the top cover can always be replaced.